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Sniff MCP server

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by sniff.world·world.sniff/sniff-mcp·v1.1.0
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Canine genomics for agents: breed allele frequencies, AI pathogenicity + OMIA clinical disease layer

B79/100grade B
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Sniff tools (18)

write = sends, deletes, buys or posts
  • askFree

    Ask Sniff a natural-language canine-genetics question and get a GROUNDED, CITED answer (or an honest abstain). Covers inherited diseases (OMIA) and their human homologs (the dog<->human disease bridge), breed disease/carrier risk, variant pathogenicity grades (AVCG; Boeykens et al. 2024, curated in OMIA), longevity/life-expectancy (McMillan 2024), temperament (Darwin's Ark/Morrill 2022, with breed-explains-X% caveats), and genetic diversity. The engine answers ONLY from cited Sniff atoms and returns `abstained: true` if it lacks grounded data — it never guesses. Educational, not diagnostic (carrier != affected; advise a vet). Returns {answer, citations:[atom_ids], abstained}. USE THIS for any 'what is X / does breed Y get Z / human equivalent of W' question; use the variant/breed/gene tools for structured lookups by identifier.

  • ask_the_graphFree

    THE INSTRUMENT — ask a free-form CROSS-SPECIES genetics question and get FILTERED, HONEST HINTS (never a confident guess). It compiles your question into a typed query plan over the dog<->human edge-graph, runs it deterministically, and scores each answer PATH by its weakest edge — returning ranked hints with an evidence TIER (fact / computational / inferred) + citations, or an honest ABSTAIN with a demand signal when the graph can't answer. BEST FOR model-discovery / translational traversal: 'which dog breeds or genes model human <disease>', 'what is the dog ortholog of <gene>', 'what dog disease is phenotypically like <human disease>'. Answers are HYPOTHESIS-GENERATING, not clinical claims: a `fact` hint = an OMIA-curated model-of; a `computational` hint = a conserved 1:1 dog ortholog (a candidate — never 'dogs get this disease'); `inferred` = shared cross-species phenotype. Returns {plan (what it asked the graph), hints:[{answer, tier, score, path (the cited edges), weakest_edge, provenance}], abstain, demand_signal}. Set narrate=true for a gated one-line prose summary per hint (faithful-or-honest-template; it can never fabricate). Use `ask` instead for owner-facing breed/disease/carrier questions; use THIS for human-disease -> dog-model cross-species queries.

  • ask_variant_contextFree

    THE headline query. Given a CanFam4 position (e.g. '5:56189113'), return the variant's global + popmax frequency, breed-stratified cross-breed frequencies, ESM2/Pangolin/phyloP pathogenicity, gene context, linked diseases (v1.1), provenance, and deep links — in one call. Pass breed_context to also get that breed's AF + rank. cross_breed_full=True returns all 188 breeds (default: top_n).

  • breed_similarityFree

    Genetic distance between two breeds (top-10-PC Euclidean). Lower = more genetically similar.

  • breed_summaryFree

    Breed profile: top damaging common variants (ESM2<=-5 & breed AF>=5%), n_dogs, breed group. Descriptive only — not a health ranking.

  • breed_variant_frequencyFree

    Breed-stratified allele frequency. Give a breed (e.g. 'bernese_mountain_dog') plus either a variant position or a gene symbol. Returns AF (+ rank) for the variant, or per-variant AFs in the gene.

  • breeds_in_atlasFree

    List all 188 breeds with breed-stratified frequencies in the atlas.

  • disease_bridgeFree

    The fused OMIA disease layer as cited atoms. Give a `disease` (name or 'OMIA:001870-9615') for its genes, inheritance, human homolog (OMIM/Mondo bridge), and variant pathogenicity grade (AVCG, ACMG/AMP 5-tier, curated in OMIA) when graded. Or give a `breed` (e.g. 'doberman_pinscher') for the inherited conditions documented in that breed with carrier frequency + confidence tier + grade. Every atom carries its source + atom_id. Educational, not diagnostic.

  • disease_linksFree

    A canine inherited disease (name or OMIA id) -> its governed OMIA clinical record: mode of inheritance, causal gene(s), curated description (summary / clinical features / molecular genetics / pathology / prevalence), clinical signs as HP/MP phenotype terms (-> Monarch), the human OMIM analog + Mondo id, and the evidence base (peer-reviewed reference count + landmark study) -- plus molecular links (variants/breeds) when the KG carries them. Sourced to OMIA (CC-BY); returns a canonical sniff.world URL. Dog-only. Educational, not diagnostic. For fuzzy candidates use search_diseases.

  • disease_lookupFree

    Look up a canine inherited disease by name or OMIA id -> its governed OMIA clinical record (inheritance, causal gene(s), curated description, clinical signs, human OMIM analog + Mondo id, evidence base). Sourced to OMIA (CC-BY); returns a canonical sniff.world URL. Dog-only. For candidate disambiguation use search_diseases; for a disease's molecular links use disease_links.

  • gene_summaryFree

    Variants in a gene (by gene symbol), ranked by impact then ESM2 damage. Paginated (limit, default 25); returns total_variants. Use af_min to filter by global AF.

  • genes_indexedFree

    Top genes by number of variants in the atlas (discovery aid).

  • metadataFree

    Atlas metadata: release, DOI, assembly, variant/breed counts, scope banner, and the RPC catalog.

  • nearest_breedsFree

    Genetically nearest breeds to the given breed (top-10-PC Euclidean in canine genetic space). Answers 'what breeds are most genetically similar to X?' via the PCA-256 breed co-embedding.

  • search_diseasesFree

    Search the canine disease catalogue by free text -> ranked candidates [{omia_id, disease, url, score}]. Use before disease_lookup when the exact name is unknown. Dog-only.

  • semantic_searchFree

    Faceted hybrid + semantic-ranker search over the whole knowledge base (diseases, breeds, Scout discoveries). Use for fuzzy/thematic intent ('drug sensitivity in herding dogs', 'breeds prone to eye disease', 'genetically diverse breeds'). entity_type filters to 'disease'|'breed'|'discovery'. filters is an OData facet expression for cross-dimension queries, e.g. "breed_group eq 'herding' and cohort_n ge 30" or "diversity_tier eq 'severe_bottleneck'" (facets: type, breed, breed_group, gene, evidence_tier, confidence_tier, diversity_tier, cohort_n). Returns ranked entities with snippets, dimension fields, links.

  • variant_lookupFree

    Single-variant lookup by CanFam4 position: ref/alt, global + popmax AF, consequence, gene, ESM2/Pangolin/phyloP, deleteriousness tier, canonical URL, provenance.

  • variant_searchFree

    Filtered discovery over all 9.67M variants. Predicates (combine freely): esm_max (ESM2 LLR <=), phylop_min (phyloP >=), popmax_min (popmax AF >=), gene_in (list of gene symbols), consequence, impact (HIGH/MODERATE/LOW/MODIFIER). Returns total_count + a capped list (max 200). Note: popmax may be in a wild population (dingo/village) — check popmax_breed.

Public scan report

scanner v0.1.9 · 2026-09-26 · same rubric, same numbers if you re-run it

no findings
  • –Code scanremote-only server, no package to scann/a
  • Live reliabilityremote reachable in 2052ms17/20
  • Tool poisoning18 tool descriptions checked15/15
  • Auth qualityopen endpoint, read-only tools10/15
  • Maintenancelast push 86 days ago12/15
  • Maintainer identitynamespace and repository owner differ; website matches verified namespace5/10
Overall 79/100. Components that don't apply are left out of the denominator. Any critical finding is an F.RubricAppeal a findingJSON

How Sniff compares

Against every graded MCP server, from our own scans and uptime checks. Updated after each scan run.

Safety score
79/100
higher than 58% of 48,255 servers
Tools
18
the typical server has 7
Tools that change things
0%
typical: 0%. Fewer write tools means less an agent can break
Uptime
100%
of our recent checks; the typical remote server answers 100%
Response time
1,034 ms
faster than 10% of 30,031 servers

What its tools let an agent do: 18 read

Install Sniff in Claude Code, Cursor or VS Code

claude mcp add --transport http sniff-mcp https://mcp.sniff.world/mcp/
Add to Cursor

What the publisher says

From the Sniff repository's README, as published. We do not edit it. Read it on GitHub

sniff-mcp — agent-callable canine genomics

The reference layer for dog DNA. A live, open API + MCP server over the Sniff Atlas — breed-stratified allele frequencies for 9,667,790 variants across 188 dog breeds (CanFam4), calibrated AI pathogenicity (ESM2, AUC 0.935 vs OMIA), Pangolin splice, Zoonomia phyloP conservation, and a variant ⇄ gene ⇄ breed ⇄ disease knowledge graph. Every response carries its own citation + provenance.

Building anything with dogs, breeds, or canine health? This is the data layer. No key, no signup — point your agent or app at it and go.

  • 🔌 MCP endpoint: https://mcp.sniff.world/mcp/ (Streamable HTTP, 15 tools) — including ask, a grounded canine-genetics Q&A that answers only from cited data or honestly abstains (no hallucinated dog-health advice), and diseasebridge** (inherited-disease atoms with ACMG-style pathogenicity grades + the dog⇄human homolog)
  • 🌐 REST API: https://api.sniff.world/ (OpenAPI docs · llms.txt)
  • 📚 Dataset: 10.5281/zenodo.20566358 (CC-BY-4.0)

Add it to your coding agent (copy-paste)

The hosted server is open and needs no auth. Pick your tool:

Claude Code

claude mcp add --transport http sniff https://mcp.sniff.world/mcp/

Cursor / Windsurf / VS Code — add to your MCP config (.cursor/mcp.json, mcp.json, etc.):

{
  "mcpServers": {
    "sniff": { "url": "https://mcp.sniff.world/mcp/" }
  }
}

Claude Desktop or any stdio-only client (uses the hosted server via a local bridge):

{
  "mcpServers": {
    "sniff": { "command": "npx", "args": ["-y", "sniff-mcp"] }
  }
}

That's it. Ask your agent: "What's the frequency of CPT2 5:56189113 across breeds?" or "Find HIGH-impact variants in DLA genes."

Use the REST API (for web apps)

No SDK needed — it's plain HTTP/JSON.

curl https://api.sniff.world/v1/variant/5:56189113
{
  "variant_id": "5:56189113", "ref": "A", "alt": "G",
  "global_af": 0.0185, "popmax_af": 0.591, "popmax_breed": "akita",
  "consequence": "missense_variant", "impact": "MODERATE",
  "gene": "CPT2", "esm2_llr": -6.1, "deleteriousness_tier": "...",
  "provenance": { "dataset_doi": "10.5281/zenodo.20566358",
                  "predicted_disease_relevance": "UNPROVEN", "...": "..." }
}
// JavaScript / TypeScript
const r = await fetch("https://api.sniff.world/v1/variant/5:56189113/context?breed=akita");
const ctx = await r.json(); // frequency + pathogenicity + gene + cross-breed + provenance

Shortened. The full README is on GitHub.

Nothing above is checked by us. What we check is on the safety report.

Sniff: common questions

Is Sniff MCP server safe?
Mostly: it is graded B (79/100). Read the Sniff safety report
How do I install Sniff?
It runs remotely at mcp.sniff.world. Add it to Claude Code, Cursor, VS Code or Claude Desktop with the snippets above, or call it through the mcp.market gateway without installing anything.
Does Sniff need an API key?
Not as far as the registry entry and our scan can tell: no credentials are declared or required.
Is Sniff maintained?
The last commit was 125 days ago (2026-07-02). The latest release is v1.1.0.
Is Sniff up?
100% of our last 28 checks got an answer. We check remote servers about four times a day.
How does Sniff compare with other MCP servers?
safety score 79/100 (higher than 58% of 48,255 servers); tools 18 (the typical server has 7); tools that change things 0% (typical: 0%. Fewer write tools means less an agent can break). Full comparison.