{"name":"world.sniff/sniff-mcp","slug":"sniff-mcp","title":null,"description":"Canine genomics for agents: breed allele frequencies, AI pathogenicity + OMIA clinical disease layer","url":"https://mcp.market/server/sniff-mcp","rating":null,"grade":"B","score":79,"certified":false,"status":"active","category":"other","tags":[],"presence":{"score":18,"stars":0,"forks":0,"downloads_week":null,"last_push_at":"2026-07-02T05:01:12.000Z","license":"MIT"},"uptime":{"percent":100,"checks":28,"ok":28,"last_checked_at":"2026-11-04T02:26:03.179Z","last_ok_at":"2026-11-04T02:26:03.179Z","latency_ms":1034},"claimed":false,"transport":"remote","callable_via_gateway":true,"default_price_micros":0,"repository":"https://github.com/Sniffscore/sniff-mcp","website":"https://sniff.world","version":"1.1.0","remotes":[{"type":"streamable-http","url":"https://mcp.sniff.world/mcp/"}],"packages":[],"tools":[{"name":"ask","description":"Ask Sniff a natural-language canine-genetics question and get a GROUNDED, CITED answer (or an honest\nabstain). Covers inherited diseases (OMIA) and their human homologs (the dog<->human disease bridge),\nbreed disease/carrier risk, variant pathogenicity grades (AVCG; Boeykens et al. 2024, curated in OMIA),\nlongevity/life-expectancy (McMillan 2024), temperament (Darwin's Ark/Morrill 2022, with breed-explains-X%\ncaveats), and genetic diversity. The engine answers ONLY from cited Sniff atoms and returns\n`abstained: true` if it lacks grounded data — it never guesses. Educational, not diagnostic\n(carrier != affected; advise a vet). Returns {answer, citations:[atom_ids], abstained}. USE THIS for any\n'what is X / does breed Y get Z / human equivalent of W' question; use the variant/breed/gene tools for\nstructured lookups by identifier.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"question":{"type":"string"}},"required":["question"],"additionalProperties":false}},{"name":"ask_the_graph","description":"THE INSTRUMENT — ask a free-form CROSS-SPECIES genetics question and get FILTERED, HONEST HINTS (never a\nconfident guess). It compiles your question into a typed query plan over the dog<->human edge-graph, runs it\ndeterministically, and scores each answer PATH by its weakest edge — returning ranked hints with an evidence\nTIER (fact / computational / inferred) + citations, or an honest ABSTAIN with a demand signal when the graph\ncan't answer. BEST FOR model-discovery / translational traversal: 'which dog breeds or genes model human\n<disease>', 'what is the dog ortholog of <gene>', 'what dog disease is phenotypically like <human disease>'.\nAnswers are HYPOTHESIS-GENERATING, not clinical claims: a `fact` hint = an OMIA-curated model-of; a\n`computational` hint = a conserved 1:1 dog ortholog (a candidate — never 'dogs get this disease'); `inferred`\n= shared cross-species phenotype. Returns {plan (what it asked the graph), hints:[{answer, tier, score,\npath (the cited edges), weakest_edge, provenance}], abstain, demand_signal}. Set narrate=true for a gated\none-line prose summary per hint (faithful-or-honest-template; it can never fabricate). Use `ask` instead for\nowner-facing breed/disease/carrier questions; use THIS for human-disease -> dog-model cross-species queries.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"question":{"type":"string"},"narrate":{"default":false,"type":"boolean"}},"required":["question"],"additionalProperties":false}},{"name":"ask_variant_context","description":"THE headline query. Given a CanFam4 position (e.g. '5:56189113'), return the variant's global +\npopmax frequency, breed-stratified cross-breed frequencies, ESM2/Pangolin/phyloP pathogenicity, gene\ncontext, linked diseases (v1.1), provenance, and deep links — in one call. Pass breed_context to also\nget that breed's AF + rank. cross_breed_full=True returns all 188 breeds (default: top_n).","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"position":{"type":"string"},"breed_context":{"default":"","type":"string"},"top_n":{"default":5,"type":"integer"},"cross_breed_full":{"default":false,"type":"boolean"}},"required":["position"],"additionalProperties":false}},{"name":"breed_similarity","description":"Genetic distance between two breeds (top-10-PC Euclidean). Lower = more genetically similar.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"breed_a":{"type":"string"},"breed_b":{"type":"string"}},"required":["breed_a","breed_b"],"additionalProperties":false}},{"name":"breed_summary","description":"Breed profile: top damaging common variants (ESM2<=-5 & breed AF>=5%), n_dogs, breed group.\nDescriptive only — not a health ranking.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"breed":{"type":"string"}},"required":["breed"],"additionalProperties":false}},{"name":"breed_variant_frequency","description":"Breed-stratified allele frequency. Give a breed (e.g. 'bernese_mountain_dog') plus either a\nvariant position or a gene symbol. Returns AF (+ rank) for the variant, or per-variant AFs in the gene.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"breed":{"type":"string"},"variant":{"default":"","type":"string"},"gene":{"default":"","type":"string"}},"required":["breed"],"additionalProperties":false}},{"name":"breeds_in_atlas","description":"List all 188 breeds with breed-stratified frequencies in the atlas.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{},"additionalProperties":false}},{"name":"disease_bridge","description":"The fused OMIA disease layer as cited atoms. Give a `disease` (name or 'OMIA:001870-9615') for its\ngenes, inheritance, human homolog (OMIM/Mondo bridge), and variant pathogenicity grade (AVCG, ACMG/AMP\n5-tier, curated in OMIA) when graded. Or give a `breed` (e.g. 'doberman_pinscher') for the inherited\nconditions documented in that breed with carrier frequency + confidence tier + grade. Every atom carries\nits source + atom_id. Educational, not diagnostic.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"disease":{"default":"","type":"string"},"breed":{"default":"","type":"string"}},"additionalProperties":false}},{"name":"disease_links","description":"A canine inherited disease (name or OMIA id) -> its governed OMIA clinical record: mode of inheritance,\ncausal gene(s), curated description (summary / clinical features / molecular genetics / pathology /\nprevalence), clinical signs as HP/MP phenotype terms (-> Monarch), the human OMIM analog + Mondo id, and\nthe evidence base (peer-reviewed reference count + landmark study) -- plus molecular links (variants/breeds)\nwhen the KG carries them. Sourced to OMIA (CC-BY); returns a canonical sniff.world URL. Dog-only.\nEducational, not diagnostic. For fuzzy candidates use search_diseases.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"disease":{"default":"","type":"string"}},"additionalProperties":false}},{"name":"disease_lookup","description":"Look up a canine inherited disease by name or OMIA id -> its governed OMIA clinical record (inheritance,\ncausal gene(s), curated description, clinical signs, human OMIM analog + Mondo id, evidence base). Sourced\nto OMIA (CC-BY); returns a canonical sniff.world URL. Dog-only. For candidate disambiguation use\nsearch_diseases; for a disease's molecular links use disease_links.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"query":{"type":"string"}},"required":["query"],"additionalProperties":false}},{"name":"gene_summary","description":"Variants in a gene (by gene symbol), ranked by impact then ESM2 damage. Paginated (limit, default 25);\nreturns total_variants. Use af_min to filter by global AF.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"gene_symbol":{"type":"string"},"af_min":{"default":0,"type":"number"},"limit":{"default":25,"type":"integer"}},"required":["gene_symbol"],"additionalProperties":false}},{"name":"genes_indexed","description":"Top genes by number of variants in the atlas (discovery aid).","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"limit":{"default":50,"type":"integer"}},"additionalProperties":false}},{"name":"metadata","description":"Atlas metadata: release, DOI, assembly, variant/breed counts, scope banner, and the RPC catalog.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{},"additionalProperties":false}},{"name":"nearest_breeds","description":"Genetically nearest breeds to the given breed (top-10-PC Euclidean in canine genetic space).\nAnswers 'what breeds are most genetically similar to X?' via the PCA-256 breed co-embedding.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"breed":{"type":"string"},"k":{"default":10,"type":"integer"}},"required":["breed"],"additionalProperties":false}},{"name":"search_diseases","description":"Search the canine disease catalogue by free text -> ranked candidates [{omia_id, disease, url, score}].\nUse before disease_lookup when the exact name is unknown. Dog-only.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"query":{"type":"string"},"limit":{"default":10,"type":"integer"}},"required":["query"],"additionalProperties":false}},{"name":"semantic_search","description":"Faceted hybrid + semantic-ranker search over the whole knowledge base (diseases, breeds, Scout\ndiscoveries). Use for fuzzy/thematic intent ('drug sensitivity in herding dogs', 'breeds prone to eye\ndisease', 'genetically diverse breeds'). entity_type filters to 'disease'|'breed'|'discovery'. filters\nis an OData facet expression for cross-dimension queries, e.g. \"breed_group eq 'herding' and cohort_n ge 30\"\nor \"diversity_tier eq 'severe_bottleneck'\" (facets: type, breed, breed_group, gene, evidence_tier,\nconfidence_tier, diversity_tier, cohort_n). Returns ranked entities with snippets, dimension fields, links.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"query":{"type":"string"},"top_k":{"default":8,"type":"integer"},"entity_type":{"default":"","type":"string"},"filters":{"default":"","type":"string"}},"required":["query"],"additionalProperties":false}},{"name":"variant_lookup","description":"Single-variant lookup by CanFam4 position: ref/alt, global + popmax AF, consequence, gene,\nESM2/Pangolin/phyloP, deleteriousness tier, canonical URL, provenance.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"position":{"type":"string"}},"required":["position"],"additionalProperties":false}},{"name":"variant_search","description":"Filtered discovery over all 9.67M variants. Predicates (combine freely): esm_max (ESM2 LLR <=),\nphylop_min (phyloP >=), popmax_min (popmax AF >=), gene_in (list of gene symbols), consequence,\nimpact (HIGH/MODERATE/LOW/MODIFIER). Returns total_count + a capped list (max 200). Note: popmax may\nbe in a wild population (dingo/village) — check popmax_breed.","write_action":false,"price_micros":0,"input_schema":{"type":"object","properties":{"esm_max":{"default":null,"type":"number"},"phylop_min":{"default":null,"type":"number"},"popmax_min":{"default":null,"type":"number"},"gene_in":{"default":null,"items":{"type":"string"},"type":"array"},"consequence":{"default":"","type":"string"},"impact":{"default":"","type":"string"},"limit":{"default":50,"type":"integer"}},"additionalProperties":false}}],"scan":{"score":79,"grade":"B","scanned_at":"2026-09-26T11:38:37.948Z","report":{"scannerVersion":"0.1.9","scannedAt":"2026-09-26T11:38:38.041Z","components":{"code":{"score":-1,"max":25,"notes":["remote-only server, no package to scan"]},"reliability":{"score":17,"max":20,"notes":["remote reachable in 2052ms"]},"poisoning":{"score":15,"max":15,"notes":["18 tool descriptions checked"]},"auth":{"score":10,"max":15,"notes":["open endpoint, read-only tools"]},"maintenance":{"score":12,"max":15,"notes":["last push 86 days ago"]},"identity":{"score":5,"max":10,"notes":["namespace and repository owner differ","website matches verified namespace"]}},"findings":[],"inputs":{"probes":[{"url":"https://mcp.sniff.world/mcp/","reachable":true,"authRequired":false,"latencyMs":2052,"serverInfo":{"name":"Sniff","version":"3.4.2"}}],"packages":[],"repo":{"found":true,"owner":"Sniffscore","repo":"sniff-mcp","archived":false,"pushedAt":"2026-07-02T05:01:12Z","stars":0,"forks":0,"openIssues":0,"ownerType":"User","ownerAvatarUrl":"https://avatars.githubusercontent.com/u/286541468?v=4","ownerCreatedAt":"2026-05-21T04:01:36Z","license":"MIT"},"icon":{"url":"https://sniff.world/favicon.svg","source":"site"},"presence":{"stars":0,"forks":0,"downloadsWeek":null,"license":"MIT","lastPushAt":"2026-07-02T05:01:12.000Z","score":18}}}},"grade_history":[],"reviews":[]}