Aria MCP server
io.github.pkotecha-eng/aria-mcp-server·v0.2.1·3 starsSearch 35M+ PubMed, 400K+ ClinicalTrials.gov & ISRCTN trials. Prompts included. No API key.
3 stars30 downloads/wk
Reviews
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If you have run it, two minutes of your experience saves the next person an afternoon.
Aria tools (3)
write = sends, deletes, buys or postsRead from the package source without running it. The installed server may list more.
search_clinical_trialsSearch ClinicalTrials.gov for clinical studies.
search_isrctnSearch the ISRCTN registry for UK and European clinical trials.
search_pubmedSearch PubMed for peer-reviewed biomedical literature.
Public scan report
scanner v0.1.9 · 2026-09-26 · same rubric, same numbers if you re-run it
- Code scan5 source files scanned25/25
- –Live reliabilityno gateway calls yet and no remote to proben/a
- –Tool poisoningtools not inspected (local package is not executed); not countedn/a
- Auth qualitylocal package, no credentials required12/15
- Maintenancelast push 75 days ago12/15
- Maintainer identityregistry namespace matches repository owner6/10
How Aria compares
Against every graded Web search MCP server, from our own scans and uptime checks. Updated after each scan run.
- Safety score
- 85/100
- higher than 75% of 3,470 Web search servers
- Tools
- 3
- the typical Web search server has 5
- Tools that change things
- 0%
- typical: 0%. Fewer write tools means less an agent can break
- GitHub stars
- 3
- more than 73% of 1,786 Web search servers
- Downloads a week
- 30
- more than 16% of 827 Web search servers with a package
What its tools let an agent do: 3 read
Install Aria in Claude Code, Cursor or VS Code
claude mcp add aria-mcp-server -- uvx aria-mcp-server
What the publisher says
From the Aria repository's README, as published. We do not edit it. Read it on GitHub
<!-- mcp-name: io.github.pkotecha-eng/aria-mcp-server -->
🧬 ARIA Clinical Research MCP Server
A standalone MCP server that gives any Claude agent real-time access to biomedical literature and clinical trials — no API keys required.
Tools
Prompts
Resources
Example queries
Once connected, ask Claude:
- "Search PubMed for ketogenic diet pediatric epilepsy outcomes"
- "Find recruiting trials for lung cancer immunotherapy"
- "What does the literature say about veliparib in ovarian cancer, and are there active trials?"
- "Find UK and European trials for pediatric epilepsy via ISRCTN"
Quickstart
pip install aria-mcp-server
aria-mcp-serverConnect to Claude Desktop
Add to ~/Library/Application Support/Claude/claudedesktopconfig.json:
{
"mcpServers": {
"aria-clinical-research": {
"command": "aria-mcp-server"
}
}
}Restart Claude Desktop. The server will appear under Settings → Developer → Local MCP Servers.
Data sources
- PubMed — NCBI E-utilities (public API, no key required)
- ClinicalTrials.gov — v2 REST API (public API, no key required)
- ISRCTN — UK/European clinical trials registry (public API, no key required)
Tech stack
- FastMCP — MCP server framework
- Python 3.12+
Use cases
- Life sciences researchers needing real-time literature access
- Clinical trial coordinators checking eligibility and recruiting status
- Drug discovery teams cross-referencing published evidence with active trials
- Any Claude agent needing grounded biomedical knowledge
Project Structure
aria-mcp-server/ ← root, where mcp-publisher runs
├── aria_mcp_server/ ← Python package
│ ├── __init__.py
│ ├── server.py
│ └── tools.py
├── server.json ← MCP registry metadata
├── pyproject.toml
├── README.md
├── LICENSE
└── glama.jsonBuilt by
Pooja Kotecha · dinq.me/pkotecha-eng
Nothing above is checked by us. What we check is on the safety report.
Aria: common questions
- Is Aria MCP server safe?
- Yes, by our scan: it is graded A (85/100). Read the Aria safety report
- How do I install Aria?
- It runs on your machine. Copy the Claude Code, Cursor, VS Code or Claude Desktop config from the install section.
- Does Aria need an API key?
- Not as far as the registry entry and our scan can tell: no credentials are declared or required.
- Is Aria maintained?
- The last commit was 114 days ago (2026-07-13). The latest release is v0.2.1.
- What can I use instead of Aria?
- Servers from other publishers that do the same job: Clinicaltrialsgov MCP server, Free Search MCP server and Keyline Icons MCP server.
- How does Aria compare with other Web search MCP servers?
- safety score 85/100 (higher than 75% of 3,470 Web search servers); tools 3 (the typical Web search server has 5); tools that change things 0% (typical: 0%. Fewer write tools means less an agent can break). Full comparison.
Alternatives to Aria
Same job from other publishers: the closest match first, then the best rated.
- ClinicaltrialsgovSearch ClinicalTrials.gov: find studies, retrieve results, match patients to candidate trials.not reviewedEstablishedA
Free SearchNo-API-key web search, page fetching and document reading across many engines. Local-first.not reviewedEstablishedB- Keyline IconsSearch Keyline Icons by name and get any icon's SVG source or React import. No key, no network.not reviewedEstablishedA
- BraveVisit https://brave.com/search/api/ for a free API key. Search the web, local businesses, images,…not reviewedEstablishedA
- PubMed SearchMulti-source biomedical literature search: PubMed, Europe PMC, OpenAlex, full text, citationsnot reviewedEstablishedB