Clinicaltrialsgov MCP server

online · 100% uptime

by cyanheads·io.github.cyanheads/clinicaltrialsgov-mcp-server·v2.11.0·96 stars

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Search ClinicalTrials.gov: find studies, retrieve results, match patients to candidate trials.

A93/100grade A

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Safety scan

A93/100

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Adoption

Established

96 stars2.4k downloads/wk

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Clinicaltrialsgov tools

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How Clinicaltrialsgov compares

Against every graded Web search MCP server, from our own scans and uptime checks. Updated after each scan run.

Safety score: 93/100; higher than 95% of 3,470 Web search servers
Uptime: 100%; of our recent checks; the typical remote Web search server answers 100%
Response time: 232 ms; faster than 62% of 2,238 Web search servers
GitHub stars: 96; more than 95% of 1,786 Web search servers
Downloads a week: 2,406; more than 95% of 827 Web search servers with a package

Release history: 8 versions in the registry since 2026-09-13, latest 2026-11-03, typically one every 8 days.

Install Clinicaltrialsgov in Claude Code, Cursor or VS Code

claude mcp add --transport http clinicaltrialsgov-mcp-server https://clinicaltrials.caseyjhand.com/mcp

Add to Cursor

What the publisher says

From the Clinicaltrialsgov repository's README, as published. We do not edit it. Read it on GitHub

clinicaltrialsgov-mcp-server Search ClinicalTrials.gov trials, retrieve study details and results, and match patients to eligible trials via MCP. STDIO or Streamable HTTP. 7 Tools • 1 Resource • 1 Prompt

Public Hosted Server: https://clinicaltrials.caseyjhand.com/mcp

Overview

Clinical trial data from the ClinicalTrials.gov REST API v2 — the US National Library of Medicine's registry of ~577K clinical trial studies. Search trials, fetch full study records and posted results, discover field names and valid values, and match patient demographics to eligible recruiting trials. Public, read-only, no authentication required. Runs as a stdio process, a local Streamable HTTP server, or the public hosted endpoint above.

Tools

Resources

Shortened. The full README is on GitHub.

Nothing above is checked by us. What we check is on the safety report.

Clinicaltrialsgov: common questions

Is Clinicaltrialsgov MCP server safe?: Yes, by our scan: it is graded A (93/100). Read the Clinicaltrialsgov safety report
How do I install Clinicaltrialsgov?: It runs remotely at clinicaltrials.caseyjhand.com. Add it to Claude Code, Cursor, VS Code or Claude Desktop with the snippets above, or call it through the mcp.market gateway without installing anything.
Does Clinicaltrialsgov need an API key?: No secret keys are declared. It reads 13 settings from the environment.
Is Clinicaltrialsgov maintained?: The last commit was 42 days ago (2026-09-22). The latest release is v2.11.0.
Is Clinicaltrialsgov up?: 100% of our last 28 checks got an answer. We check remote servers about four times a day.
What can I use instead of Clinicaltrialsgov?: Servers from other publishers that do the same job: Brave Search MCP server and HasData Google Scholar MCP server.
How does Clinicaltrialsgov compare with other Web search MCP servers?: safety score 93/100 (higher than 95% of 3,470 Web search servers); uptime 100% (of our recent checks; the typical remote Web search server answers 100%); response time 232 ms (faster than 62% of 2,238 Web search servers). Full comparison.

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Run it through the gateway

With the gateway added, ask your agent for it by name:

agent prompt

call io.github.cyanheads/clinicaltrialsgov-mcp-server → <tool>

Free per call. Metered, capped by your key, logged for reliability.

Add the gateway (gw.mcp.market)

Rating: —
Safety grade: A · 93/100
Stars: 96
Downloads/wk: 2.4k
Price: Free
Licence: Apache-2.0
Transport: Remote · mixed
Uptime: 100% · 28/28 checks
Version: 2.11.0
Category: Web search
Last release: 2026-09-22

Credentials it needs

CT_API_BASE_URLClinicalTrials.gov API base URL.
CT_REQUEST_TIMEOUT_MSPer-request timeout in milliseconds; a positive integer.
CT_MAX_PAGE_SIZEMost studies one clinicaltrials_search_studies page returns; an integer of at least 1, values above 1000 clamp to 1000.
MCP_LOG_LEVELSets the minimum log level for output (e.g., 'debug', 'info', 'warn').
MCP_TRANSPORT_TYPESelects the HTTP transport.
CT_API_BASE_URLClinicalTrials.gov API base URL.
CT_REQUEST_TIMEOUT_MSPer-request timeout in milliseconds; a positive integer.
CT_MAX_PAGE_SIZEMost studies one clinicaltrials_search_studies page returns; an integer of at least 1, values above 1000 clamp to 1000.
MCP_HTTP_HOSTThe hostname for the HTTP server.
MCP_HTTP_PORTThe port to run the HTTP server on.
MCP_HTTP_ENDPOINT_PATHThe endpoint path for the MCP server.
MCP_AUTH_MODEAuthentication mode to use: 'none', 'jwt', or 'oauth'.
MCP_LOG_LEVELSets the minimum log level for output (e.g., 'debug', 'info', 'warn').

Endpoint

https://clinicaltrials.caseyjhand.com/mcp

streamable-http

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