Pharma MCP server

pharma-mcp

MCP server for clinical and pharmaceutical data.

Gives Claude and any MCP-compatible AI agent direct access to:

• ClinicalTrials.gov — search and retrieve trial protocols, endpoints, eligibility criteria
• PubMed — literature search with MeSH terms, full abstracts, citation formatting
• FDA openFDA — drug labels, approved indications, warnings, boxed warnings
• FDA FAERS — adverse event reports with patient demographics and outcomes
• ICH Guidelines — structured summaries of E3, E6, E9, M4, Q1A, and more

No API keys required. All data sources are public. Runs locally in under 60 seconds.

Tools

Quickstart

Install

git clone https://github.com/pubspro/pharma-mcp.git
cd pharma-mcp
npm install

Add to Claude Desktop

Edit ~/Library/Application Support/Claude/claudedesktopconfig.json (macOS) or %APPDATA%\Claude\claudedesktopconfig.json (Windows):

{
  "mcpServers": {
    "pharma-mcp": {
      "command": "node",
      "args": ["/absolute/path/to/pharma-mcp/src/index.js"]
    }
  }
}

Restart Claude Desktop. The tools appear automatically.

Add to Claude Code

claude mcp add pharma-mcp node /absolute/path/to/pharma-mcp/src/index.js

Example prompts

Once connected, ask Claude:

Search ClinicalTrials.gov for Phase 3 recruiting trials for non-small cell lung cancer involving osimertinib.

Find the 10 most recent PubMed papers on GLP-1 receptor agonists and cardiovascular outcomes. Format citations in Vancouver style.

Get the FDA label for semaglutide — what are the boxed warnings and contraindications?

What does ICH E3 require for a clinical study report? Which sections are mandatory?

Pull adverse event reports for dupilumab involving anaphylaxis from FAERS.

Use cases

Medical writers and publications teams

• Rapid literature gap analysis for advisory boards and manuscripts
• Auto-format reference lists from PubMed searches
• Check ICH E3 requirements mid-draft without switching tabs

Regulatory affairs

• Search FDA labels for labeling precedent
• Check FAERS signal for benefit-risk narratives
• Retrieve ICH guideline requirements for CTD modules

Clinical development

• Competitive landscape searches across ClinicalTrials.gov
• Identify comparable trial designs and endpoints

AI agent pipelines

• Chain pharma-mcp tools with other MCP servers for autonomous regulatory research workflows

Data sources

All data retrieved in real time from official public APIs — no data stored, no API keys required:

• ClinicalTrials.gov API v2
• NCBI E-utilities (PubMed)
• openFDA API
• ICH Guidelines

Requirements

• Node.js 18+
• npm

Roadmap

• [ ] EMA EPAR search
• [ ] DailyMed full prescribing information
• [ ] GPP4 / ICMJE authorship criteria checker
• [ ] ClinVar genetic variant lookup

PRs and issues welcome.

License

MIT