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Tooluniverse MCP server

by mims-harvard·io.github.mims-harvard/tooluniverse·v1.5.8·1.7k stars
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2,700+ scientific tools for AI scientists: life science, research, literature, and more.

C69/100grade C
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C69/100

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1.7k stars12k downloads/wk

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Tooluniverse tools

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How Tooluniverse compares

Against every graded MCP server, from our own scans and uptime checks. Updated after each scan run.

Safety score
69/100
higher than 33% of 48,255 servers
GitHub stars
1,737
more than 95% of 28,688 servers
Downloads a week
12,153
more than 95% of 12,191 servers with a package

Release history: 7 versions in the registry since 2026-09-16, latest 2026-11-01, typically one every 7 days.

Install Tooluniverse in Claude Code, Cursor or VS Code

claude mcp add tooluniverse -- uvx tooluniverse
Add to Cursor

What the publisher says

From the Tooluniverse repository's README, as published. We do not edit it. Read it on GitHub

ToolUniverse: Democratizing AI scientists

[//]: # (mcp-name: io.github.mims-harvard/tooluniverse)

Install

[!IMPORTANT]

Claude Desktop extension showing "Failed — Server disconnected"? The copy of ToolUniverse in

Claude Desktop's built-in Extensions directory is an old build that cannot start. Remove it, then

use either option below — both install a working version.

Details and status: #585

AI agent (recommended) — open your AI agent and run:

Read https://aiscientist.tools/setup.md and set up ToolUniverse for me.

The agent will walk you through MCP configuration, API keys, skill installation, and validation.

or set up manually

Add to your MCP config file:

{
  "mcpServers": {
    "tooluniverse": {
      "command": "uvx",
      "args": ["--refresh", "tooluniverse"],
      "env": {"PYTHONIOENCODING": "utf-8"}
    }
  }
}

--refresh checks PyPI for the newest release on every launch. Drop it ("args": ["tooluniverse"]) to start faster from uv's cache — then upgrade with uv cache clean tooluniverse.

Install agent skills:

npx skills add mims-harvard/ToolUniverse

Claude Code users — one line, no config file:

claude plugin marketplace add mims-harvard/ToolUniverse
claude plugin install tooluniverse@tooluniverse

Python developers — install the SDK. Install uv first and do not use system pip: on a current Mac, pip install tooluniverse fails with externally-managed-environment (PEP 668) and python3 -m venv can fail at ensurepip. uv manages its own Python and avoids both.

curl -LsSf https://astral.sh/uv/install.sh | sh   # if you don't have uv
uv venv --python 3.12 && source .venv/bin/activate
uv pip install tooluniverse

The base install covers the API and database tools. Local ML, cheminformatics, and plotting tools need extras — uv pip install 'tooluniverse[all]', or a single group such as [ml], [visualization], [bioinformatics]. Note [all] excludes pdf, singlecell, smolagents, client, and build, which install by name. Run tooluniverse-doctor to see which groups are missing.

tu CLI — discover, inspect, run, and test tools from the terminal. Python SDK — programmatic access for building AI scientist systems.

Building AI Scientists with ToolUniverse

Shortened. The full README is on GitHub.

Nothing above is checked by us. What we check is on the safety report.

Grade history

  • 2026-09-19restoreD → Cscore 69: Network call to a raw IP address; eval / new Function used

Tooluniverse: common questions

Is Tooluniverse MCP server safe?
With care: it is graded C, so read the findings first (69/100). Read the Tooluniverse safety report
How do I install Tooluniverse?
It runs on your machine. Copy the Claude Code, Cursor, VS Code or Claude Desktop config from the install section.
Does Tooluniverse need an API key?
Yes. The registry entry asks for OPENAI_API_KEY, ANTHROPIC_API_KEY, GEMINI_API_KEY, OPENROUTER_API_KEY and 12 more.
Is Tooluniverse maintained?
The last commit was 20 days ago (2026-10-15). The latest release is v1.5.8.
What can I use instead of Tooluniverse?
Servers from other publishers that do the same job: Knowl MCP server.
How does Tooluniverse compare with other MCP servers?
safety score 69/100 (higher than 33% of 48,255 servers); github stars 1,737 (more than 95% of 28,688 servers); downloads a week 12,153 (more than 95% of 12,191 servers with a package). Full comparison.

Alternatives to Tooluniverse

Same job from other publishers: the closest match first, then the best rated.

  • Knowl
    Persistent memory for AI agents, for code, research and everyday life. Stale facts retire.
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