Uniprot MCP server
online · 100% uptimeProtein research over UniProtKB: search by function, fetch curated records, map IDs, proteomes.
not scanned yet
2 stars954 downloads/wk
Reviews
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If you have run it, two minutes of your experience saves the next person an afternoon.
Uniprot tools
Tool list not cached yet. `describe` through the gateway fetches it live.
How Uniprot compares
Against every graded Web search MCP server, from our own scans and uptime checks. Updated after each scan run.
- Safety score
- 93/100
- higher than 95% of 3,470 Web search servers
- Uptime
- 100%
- of our recent checks; the typical remote Web search server answers 100%
- Response time
- 512 ms
- faster than 29% of 2,238 Web search servers
- GitHub stars
- 2
- more than 70% of 1,786 Web search servers
- Downloads a week
- 954
- more than 95% of 827 Web search servers with a package
Release history: 6 versions in the registry since 2026-08-30, latest 2026-11-04, typically one every 13 days.
Install Uniprot in Claude Code, Cursor or VS Code
claude mcp add --transport http uniprot-mcp-server https://uniprot.caseyjhand.com/mcp
What the publisher says
From the Uniprot repository's README, as published. We do not edit it. Read it on GitHub
@cyanheads/uniprot-mcp-server Search UniProtKB by protein function, fetch curated records, map IDs across databases, and pull reference proteomes, taxonomy, and sequences via MCP. STDIO or Streamable HTTP. 6 Tools • 2 Resources • 1 Prompt
Public Hosted Server: https://uniprot.caseyjhand.com/mcp
Overview
Protein research over UniProtKB (rest.uniprot.org). Search by function or gene, fetch curated records, translate identifiers across sibling databases, and pull reference proteomes, taxonomy, and sequences from any MCP client. Runs as a stdio process, a local Streamable HTTP server, or the public hosted endpoint above.
Tools
Shortened. The full README is on GitHub.
Nothing above is checked by us. What we check is on the safety report.
Uniprot: common questions
- Is Uniprot MCP server safe?
- Yes, by our scan: it is graded A (93/100). Read the Uniprot safety report
- How do I install Uniprot?
- It runs remotely at uniprot.caseyjhand.com. Add it to Claude Code, Cursor, VS Code or Claude Desktop with the snippets above, or call it through the mcp.market gateway without installing anything.
- Does Uniprot need an API key?
- No secret keys are declared. It reads 7 settings from the environment.
- Is Uniprot maintained?
- The last commit was 22 days ago (2026-10-12). The latest release is v0.4.0.
- Is Uniprot up?
- 100% of our last 28 checks got an answer. We check remote servers about four times a day.
- What can I use instead of Uniprot?
- Servers from other publishers that do the same job: Zotero MCP server, Perplexity API Platform (moved to ai.perplexity/mcp-server) and Perplexity API Platform MCP server.
- How does Uniprot compare with other Web search MCP servers?
- safety score 93/100 (higher than 95% of 3,470 Web search servers); uptime 100% (of our recent checks; the typical remote Web search server answers 100%); response time 512 ms (faster than 29% of 2,238 Web search servers). Full comparison.
Alternatives to Uniprot
Same job from other publishers: the closest match first, then the best rated.
Zotero MCPSearch, read, annotate, and add to your Zotero research library, local or web.not reviewedWidely usedB- Perplexity API Platform (moved to ai.perplexity/mcp-server)Real-time web search, reasoning, and research through Perplexity's APInot reviewedWidely usedA
- Perplexity API PlatformReal-time web search, reasoning, and research through Perplexity's APInot reviewedEstablishedA
- webclawWeb scraping, search, crawling, structured extraction and research for AI agents.not reviewedEstablishedA
- Google Maps MCP Server18 Google Maps tools for AI agents — geocode, search, directions, weather, and more.not reviewedEstablishedB
