MCP.Market

Pubchem MCP server

online · 100% uptime
by cyanheads·io.github.cyanheads/pubchem-mcp-server·v0.8.0·9 stars
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Search PubChem compounds, properties, safety data, bioactivity, and cross-references.

A93/100grade A
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Safety scan
A93/100

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Adoption
Established

9 stars1.7k downloads/wk

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Pubchem tools

Tool list not cached yet. `describe` through the gateway fetches it live.

Not scanned yet. New listings are scanned within a day or two of arriving.

How Pubchem compares

Against every graded Web search MCP server, from our own scans and uptime checks. Updated after each scan run.

Safety score
93/100
higher than 95% of 3,470 Web search servers
Uptime
100%
of our recent checks; the typical remote Web search server answers 100%
Response time
504 ms
faster than 29% of 2,238 Web search servers
GitHub stars
9
more than 85% of 1,786 Web search servers
Downloads a week
1,668
more than 95% of 827 Web search servers with a package

Release history: 8 versions in the registry since 2026-09-13, latest 2026-10-28, typically one every 6 days.

Install Pubchem in Claude Code, Cursor or VS Code

claude mcp add --transport http pubchem-mcp-server https://pubchem.caseyjhand.com/mcp
Add to Cursor

What the publisher says

From the Pubchem repository's README, as published. We do not edit it. Read it on GitHub

@cyanheads/pubchem-mcp-server Search the PubChem chemical database for compounds, properties, safety data, bioactivity, cross-references, and entity summaries via MCP. STDIO or Streamable HTTP. 10 Tools • 6 Resources

Public Hosted Server: https://pubchem.caseyjhand.com/mcp

Overview

Chemical compound and bioassay data from PubChem's PUG REST and PUG View APIs. Search compounds by identifier, formula, or structure; fetch physicochemical properties, safety data, bioactivity, interactions, cross-references, and 3D structures; find bioassays by biological target. Runs as a stdio process, a local Streamable HTTP server, or the public hosted endpoint above.

Tools

Shortened. The full README is on GitHub.

Nothing above is checked by us. What we check is on the safety report.

Pubchem: common questions

Is Pubchem MCP server safe?
Yes, by our scan: it is graded A (93/100). Read the Pubchem safety report
How do I install Pubchem?
It runs remotely at pubchem.caseyjhand.com. Add it to Claude Code, Cursor, VS Code or Claude Desktop with the snippets above, or call it through the mcp.market gateway without installing anything.
Does Pubchem need an API key?
No secret keys are declared. It reads 8 settings from the environment.
Is Pubchem maintained?
The last commit was 40 days ago (2026-09-25). The latest release is v0.8.0.
Is Pubchem up?
100% of our last 28 checks got an answer. We check remote servers about four times a day.
What can I use instead of Pubchem?
Servers from other publishers that do the same job: Claude Code Ultimate Guide MCP server and fojin — Buddhist Canon Tools MCP server.
How does Pubchem compare with other Web search MCP servers?
safety score 93/100 (higher than 95% of 3,470 Web search servers); uptime 100% (of our recent checks; the typical remote Web search server answers 100%); response time 504 ms (faster than 29% of 2,238 Web search servers). Full comparison.

Alternatives to Pubchem

Same job from other publishers: the closest match first, then the best rated.

  • Claude Code Ultimate Guide
    Search the Claude Code Ultimate Guide and machine-readable references from any MCP client.
    A
  • fojin — Buddhist Canon Tools
    Buddhist canon tools: search, passages, cross-canon parallels, dictionaries — all URN-cited.
    A

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