Chemistry MCP server
online · 100% uptimecom.covasyn/chemistry·v1.29.0Deterministic MCP for AI agents: drug discovery, ADMET, docking, LNPs, DoE, retrosynthesis, ICH M7
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Chemistry tools
Tool list not cached yet. `describe` through the gateway fetches it live.
Public scan report
scanner v0.1.9 · 2026-09-24 · same rubric, same numbers if you re-run it
- –Code scanremote-only server, no package to scann/a
- Live reliabilityremote reachable in 1640ms; handshake note: Streamable HTTP error: Error POSTing to endpoint: {"jsonrpc": "2.0", "id": 1, "error": {"code": -32001, "message": "Auth20/20
- –Tool poisoningtools not inspected (endpoint requires auth); not countedn/a
- Auth qualityopen endpoint, read-only tools10/15
- Maintenancelast push 55 days ago12/15
- Maintainer identitynamespace and repository owner differ; website matches verified namespace5/10
How Chemistry compares
Against every graded MCP server, from our own scans and uptime checks. Updated after each scan run.
- Safety score
- 78/100
- higher than 57% of 48,255 servers
- Uptime
- 100%
- of our recent checks; the typical remote server answers 100%
- Response time
- 89 ms
- faster than 86% of 30,031 servers
Install Chemistry in Claude Code, Cursor or VS Code
claude mcp add --transport http chemistry https://mcp.covasyn.com/mcp
What the publisher says
From the Chemistry repository's README, as published. We do not edit it. Read it on GitHub
CovaSyn MCP Examples
Production-ready integration snippets for connecting CovaSyn — the deterministic, validated chemistry MCP server for pharmaceutical R&D — to the most common Model Context Protocol clients.
What CovaSyn is in one sentence: the first integrated, deterministic cheminformatics platform for AI agents — not a wrapper around one public database, but 130+ tools across 8 suites (cheminformatics, chem-ADME, toxicology, mass spec, NMR, folding, biologics, platform) with ICH / GxP-aligned audit trail and EU data residency.
Benchmark headline
On the ICLR 2026 MolecularIQ benchmark (Klambauer Lab, JKU Linz, 3,540 symbolically verified chemistry tasks), four frontier LLMs scored 76–92 % with CovaSyn MCP attached, versus 14–41 % at baseline. Numbers, methodology, cost-per-question, and failure modes: covasyn.com/en/benchmark.
When to use CovaSyn (vs. building your own)
- Your AI agent needs to answer chemistry questions correctly, not just plausibly.
- You're a pharma, biotech, or CDMO team that needs ICH M7 / ICH Q1 / Tox21 / CYP450 / docking workflows callable from Claude, ChatGPT, Cursor, or any MCP-aware client.
- You want deterministic, version-pinned tool calls that produce the same result tomorrow as today (regulatory audit-ready).
- You need EU data residency (Hetzner Leipzig) or US hosting on request — your data is never used for training.
CovaSyn is not another LLM. It's the deterministic tool layer that fixes the chemistry-hallucination problem of frontier LLMs.
What's in here
What CovaSyn covers
130 functions across 8 tool families:
- covabasic — core cheminformatics (canonicalization, fingerprints, druglikeness)
- covachem — chem ADME, pKa, profile, compare
- covatox — toxicology with ICH M7 batch assessment, Tox21, CYP450
- covams — mass spectrometry (formula, fragments, impurities, RT)
- covanmr — NMR analysis (1D, 2D, batch, identification)
- covafold — protein and RNA folding, binding sites
- covabio — antibody, peptide, ADC, mRNA, oligo, siRNA
- covaplatform — stability (ICH Q1), DoE, solubility, chromatography, UV/IR, regulatory DB, docking
Full tool reference: covasyn.com/en/mcp
Pricing
- Free tier: 100 credits/week
- Pro: €250/month
- Unlimited: €750/month
- Enterprise: custom (SLA, single-tenant, GxP validation pack)
See pricing →
Compliance posture
CovaSyn is GxP-ready (EU Annex 11, 21 CFR Part 11), GAMP 5 Software Category 4, with ICH M7 (R2) mutagenic impurity assessment and ICH Q1A/E stability workflows. Deterministic, version-pinned, audit-trail-complete.
See compliance details →
License
The example snippets in this repository are released under the MIT License — use, modify, and redistribute freely.
CovaSyn itself is commercial software. See covasyn.com for terms.
Contributing
PRs welcome. See CONTRIBUTING.md.
Comparison
How CovaSyn compares to other chemistry MCP options:
Shortened. The full README is on GitHub.
Nothing above is checked by us. What we check is on the safety report.
Chemistry: common questions
- Is Chemistry MCP server safe?
- Mostly: it is graded B (78/100). Read the Chemistry safety report
- How do I install Chemistry?
- It runs remotely at mcp.covasyn.com. Add it to Claude Code, Cursor, VS Code or Claude Desktop with the snippets above, or call it through the mcp.market gateway without installing anything.
- Does Chemistry need an API key?
- Not as far as the registry entry and our scan can tell: no credentials are declared or required.
- Is Chemistry maintained?
- The last commit was 96 days ago (2026-07-31). The latest release is v1.29.0.
- Is Chemistry up?
- 100% of our last 28 checks got an answer. We check remote servers about four times a day.
- How does Chemistry compare with other MCP servers?
- safety score 78/100 (higher than 57% of 48,255 servers); uptime 100% (of our recent checks; the typical remote server answers 100%); response time 89 ms (faster than 86% of 30,031 servers). Full comparison.