BioCatalystFeed MCP server

BioCatalystFeed

<!-- mcp-name: io.github.biocatalystfeed/biocatalystfeed -->

Website: https://biocat.ai · Contact: contact@biocat.ai

An open-source catalyst feed for biotech: see what changed across clinical trials, FDA actions, NIH grants, papers/preprints and SEC filings for the companies and drugs you follow. Use it as a CLI, as an MCP server for AI agents (Claude, Cursor, …), or as an Apify actor.

⚠️ Not investment, legal or medical advice. Data may be incomplete, delayed or wrong; PDUFA dates are unverified

candidates from SEC filings. Always check the linked primary source.

What it does

Across tools: --exclude TERM … to drop noise, --rank for relevance ordering, and --rss / --json-feed digest files on every watch (local files you can serve or feed into any reader; nothing is emailed).

Quickstart

pip install biocatalystfeed            # or: uvx biocatalystfeed --help
source .venv/bin/activate

bcf trials search --sponsor "Viking Therapeutics" --phase PHASE3
bcf papers search --drug resmetirom --since 2026-09-01 --exclude mice rat --rank
bcf grants search --pi "Ioannou, George N" --since 2024-01-01 --no-future
bcf sec pdufa MDGL --since 2023-01-01
bcf profile Lilly MDGL "Viking Therapeutics" --md profiles.md

# watches: first run = baseline, later runs report what changed (cron it daily)
bcf trials --db bcf.db watch --name obesity --condition obesity --phase PHASE3 --rss obesity.rss
bcf papers --db bcf.db watch --name mdgl --affiliation "Madrigal Pharmaceuticals" --json-feed mdgl.feed.json

The old commands (trialwatch, fdawatch, grantwatch, paperwatch, secwatch, trialwatch-mcp) still work.

MCP server

{"mcpServers": {"biocatalystfeed": {"command": "uvx", "args": ["biocatalystfeed", "mcp"],
  "env": {"BIOCATALYSTFEED_DB": "/path/to/bcf.db"}}}}

(or point command at an installed biocatalystfeed-mcp). Listed in the official MCP Registry as io.github.biocatalystfeed/biocatalystfeed. Tools include searchtrials, sponsorpipeline, fdaapprovals, companyprofile, searchgrants, searchpapers, secpdufamentions, snapshot / changessince, and changesfeed (RSS / JSON Feed).

Configuration

Shortened. The full README is on GitHub.