Mmcp.market

literature-review skill

by K-Dense-AI·K-Dense-AI/scientific-agent-skills·47k stars·MIT

Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).

C70/100content scan

Is the literature-review skill safe?

Read the findings before you install it. We read 12 files in the folder on 2026-09-28.

  • highSKILL.md:224

    Downloads a script and runs it in one step, so what runs is whatever that server sends that day. Common for installers, and still worth a look at the address.

    curl -fsSL https://parallel.ai/install.sh | bash

Install the literature-review skill

A skill is a folder. Copy it into your agent's skills folder and the agent loads it when the task matches its description.

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git /tmp/scientific-agent-skills
mkdir -p ~/.claude/skills
cp -r /tmp/scientific-agent-skills/skills/literature-review ~/.claude/skills/literature-review
available in every project

In the Claude apps, zip the folder and upload it from the Skills settings. The folder on GitHub

The instructions your agent would load

SKILL.md as published, without the frontmatter. Read it on GitHub

Literature Review

Overview

Conduct systematic, comprehensive literature reviews following rigorous academic methodology. Search multiple literature databases, synthesize findings thematically, verify all citations for accuracy, and generate professional output documents in markdown and PDF formats.

This skill uses the parallel-web skill (parallel-cli search) as the primary web search tool for broad academic literature discovery, supplemented by specialized database access skills (gget, bioservices, datacommons-client). It provides specialized tools for citation verification, result aggregation, and document generation.

When to Use This Skill

Use this skill when:

  • Conducting a systematic literature review for research or publication
  • Synthesizing current knowledge on a specific topic across multiple sources
  • Performing meta-analysis or scoping reviews
  • Writing the literature review section of a research paper or thesis
  • Investigating the state of the art in a research domain
  • Identifying research gaps and future directions
  • Requiring verified citations and professional formatting

Visual Enhancement with Scientific Schematics

⚠️ MANDATORY: Every literature review MUST include at least 1-2 AI-generated figures using the scientific-schematics skill.

This is not optional. Literature reviews without visual elements are incomplete. Before finalizing any document:

  1. Generate at minimum ONE schematic or diagram (e.g., PRISMA flow diagram for systematic reviews)
  2. Prefer 2-3 figures for comprehensive reviews (search strategy flowchart, thematic synthesis diagram, conceptual framework)

How to generate figures:

  • Use the scientific-schematics skill to generate AI-powered publication-quality diagrams
  • Simply describe your desired diagram in natural language
  • Nano Banana Pro will automatically generate, review, and refine the schematic

How to generate schematics:

python scripts/generate_schematic.py "your diagram description" -o figures/output.png

The AI will automatically:

  • Create publication-quality images with proper formatting
  • Review and refine through multiple iterations
  • Ensure accessibility (colorblind-friendly, high contrast)
  • Save outputs in the figures/ directory

When to add schematics:

  • PRISMA flow diagrams for systematic reviews
  • Literature search strategy flowcharts
  • Thematic synthesis diagrams
  • Research gap visualization maps
  • Citation network diagrams
  • Conceptual framework illustrations
  • Any complex concept that benefits from visualization

For detailed guidance on creating schematics, refer to the scientific-schematics skill documentation.

Core Workflow

A literature review runs in seven phases, documented in full with commands and templates in references/core_workflow.md:

for the PRISMA flow.

  1. Planning and scoping — the question, inclusion and exclusion criteria, and scope.
  2. Systematic literature search — multi-database searching with recorded queries.
  3. Screening and selection — title/abstract then full-text screening with counts kept

or quality appraisal.

  1. Data extraction and quality assessment — structured extraction and risk-of-bias
  1. Synthesis and analysis — thematic or quantitative synthesis across studies.
  2. Citation verification — every citation checked against the actual source.
  3. Document generation — assembling the review with a complete bibliography.

Record every search string and date as you go: a review that cannot reproduce its own search is not systematic. Per-database search guidance and citation styles are in references/searchandcitation.md, and a full worked review is in references/example_workflow.md.

Best Practices

Search Strategy

  1. Start with parallel-web: Use parallel-cli search with academic domains for initial broad coverage before querying specialized databases
  2. Use multiple databases (minimum 3): Ensures comprehensive coverage — parallel-web counts as one source
  3. Include preprint servers: Captures latest unpublished findings
  4. Document everything: Search strings, dates, result counts for reproducibility — save all parallel-cli output to sources/
  5. Test and refine: Run pilot searches, review results, adjust search terms
  6. Sort by citations: When available, sort search results by citation count to surface influential work first
  7. Use parallel-cli extract: Fetch full content from promising URLs found during search to verify relevance before full-text screening

Screening and Selection

  1. Use multiple databases (minimum 3): Ensures comprehensive coverage
  2. Include preprint servers: Captures latest unpublished findings
  3. Document everything: Search strings, dates, result counts for reproducibility
  4. Test and refine: Run pilot searches, review results, adjust search terms

Screening and Selection

  1. Use clear criteria: Document inclusion/exclusion criteria before screening
  2. Screen systematically: Title → Abstract → Full text
  3. Document exclusions: Record reasons for excluding studies
  4. Consider dual screening: For systematic reviews, have two reviewers screen independently

Synthesis

  1. Organize thematically: Group by themes, NOT by individual studies
  2. Synthesize across studies: Compare, contrast, identify patterns
  3. Be critical: Evaluate quality and consistency of evidence
  4. Identify gaps: Note what's missing or understudied

Quality and Reproducibility

  1. Assess study quality: Use appropriate quality assessment tools
  2. Verify all citations: Run verify_citations.py script
  3. Document methodology: Provide enough detail for others to reproduce
  4. Follow guidelines: Use PRISMA for systematic reviews

Writing

  1. Be objective: Present evidence fairly, acknowledge limitations
  2. Be systematic: Follow structured template
  3. Be specific: Include numbers, statistics, effect sizes where available
  4. Be clear: Use clear headings, logical flow, thematic organization

Common Pitfalls to Avoid

  1. Single database search: Misses relevant papers; always search multiple databases
  2. No search documentation: Makes review irreproducible; document all searches
  3. Study-by-study summary: Lacks synthesis; organize thematically instead
  4. Unverified citations: Leads to errors; always run verify_citations.py
  5. Too broad search: Yields thousands of irrelevant results; refine with specific terms
  6. Too narrow search: Misses relevant papers; include synonyms and related terms
  7. Ignoring preprints: Misses latest findings; include bioRxiv, medRxiv, arXiv
  8. No quality assessment: Treats all evidence equally; assess and report quality
  9. Publication bias: Only positive results published; note potential bias
  10. Outdated search: Field evolves rapidly; clearly state search date

Integration with Other Skills

This skill works seamlessly with other scientific skills:

Web Search & Extraction (parallel-web skill — PRIMARY)

  • parallel-cli search: Broad academic and general web search with domain filtering — use for initial scoping, finding papers, citation chaining, and supplementary searches
  • parallel-cli extract: Fetch full content from paper URLs, journal websites, and preprint servers — use for reading abstracts, extracting reference lists, and verifying paper details
  • parallel-cli search --include-domains: Academic-focused search across scholarly domains (arxiv.org, pubmed, nature.com, etc.)

Database Access Skills

  • gget: PubMed, bioRxiv, COSMIC, AlphaFold, Ensembl, UniProt
  • bioservices: ChEMBL, KEGG, Reactome, UniProt, PubChem
  • datacommons-client: Demographics, economics, health statistics

Analysis Skills

  • pydeseq2: RNA-seq differential expression (for methods sections)
  • scanpy: Single-cell analysis (for methods sections)
  • anndata: Single-cell data (for methods sections)
  • biopython: Sequence analysis (for background sections)

Visualization Skills

  • matplotlib: Generate figures and plots for review
  • seaborn: Statistical visualizations

Writing Skills

  • brand-guidelines: Apply institutional branding to PDF
  • internal-comms: Adapt review for different audiences
  • venue-templates: Access venue-specific writing style guides when preparing reviews for publication

Venue-Specific Writing Styles

When preparing a literature review for a specific journal, consult the venue-templates skill for writing style guidance:

  • venuewritingstyles.md: Master style comparison across venues
  • naturesciencestyle.md: Nature/Science flowing abstract style, story-driven structure
  • cellpressstyle.md: Cell Press graphical abstracts, Highlights format
  • medicaljournalstyles.md: NEJM/Lancet/JAMA structured abstracts, PRISMA compliance

These guides help adapt your review's tone, abstract format, and structure to match the target venue's expectations.

Resources

More skills from K-Dense-AI/scientific-agent-skills

  • AadaptyvHow to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.
  • AaeonThis skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
  • AalphagenomeLook up precomputed AlphaGenome Atlas effects for any GRCh38 single-nucleotide variant (AVI score with Phred and 18 SHAP feature attributions, plus raw and quantile scores for RNA-seq, DNase, ATAC, ChIP-TF, ChIP-histone, CAGE, PRO-cap, splicing, polyadenylation and contact-map tracks), score variants or scan windows on demand with the AlphaGenome model for human and mouse (variant scoring, in silico mutagenesis, REF-versus-ALT track prediction), and build Atlas website deep links. Use when the user mentions AlphaGenome, AlphaGenome Atlas, AVI or AlphaGenome Variant Impact, DeepMind variant effect prediction, or wants to prioritise or mechanistically interpret non-coding, regulatory, splicing, enhancer, promoter, or chromatin-accessibility effects of SNVs from a VCF, credible set, or region. Research use only; not a clinical tool.
  • Aanalytical-method-validationPlan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.
  • AanndataData structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
  • AarborAutonomously improve a real artifact (code, training recipe, agent harness, data pipeline, prompt) against an objective and an evaluator, using Hypothesis Tree Refinement (HTR) from the Arbor paper. Use this whenever someone wants to iteratively optimize something over many experiments without overfitting — e.g. "get my model's eval score up", "improve this agent/harness", "tune this pipeline", "beat the baseline on this benchmark", "run a search over approaches and keep the best", "do an MLE-bench / Kaggle-style optimization", or any long-horizon "make this artifact better and don't just memorize the dev set" task. Trigger it even when the user doesn't say "Arbor" or "hypothesis tree" but describes repeated experiment-and-evaluate loops, branching exploration of competing ideas, or worries about a dev/test gap. Runs Claude itself as the coordinator with subagent executors in isolated git worktrees; for the standalone `arbor` CLI tool see references/arbor-upstream.md.
  • AarboretoInfer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
  • AastropyCore Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.
  • AautoskillObserve the user's screen via screenpipe, detect repeated research workflows, match them against existing scientific-agent-skills, and draft new skills (or composition recipes that chain existing ones) for the patterns not yet covered. Use when the user asks to analyze their recent work and propose skills based on what they actually do. Requires the screenpipe daemon (https://github.com/screenpipe/screenpipe) running locally on port 3030 — the skill has no other data source and will refuse to run if screenpipe is unreachable. All detection runs locally; only redacted cluster summaries reach the LLM.
  • Abenchling-integrationBenchling Python SDK and REST API integration for registry entities, inventory, ELN entries, workflows, Benchling Apps, and Data Warehouse queries. Use when automating lab data with benchling-sdk or the v2 API.
  • Abgpt-paper-searchSearch scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.
  • AbidsUse this skill when working with Brain Imaging Data Structure (BIDS) datasets: organizing neuroscience and biomedical data (MRI, EEG, MEG, iEEG, PET, microscopy, NIRS, motion capture, EMG, MR spectroscopy, behavioral), querying BIDS layouts, validating compliance, converting DICOM to BIDS, writing metadata sidecars, or creating BIDS derivatives.

All agent skills → · MCP servers