Folklore Clinical Variant Interpretation MCP server

• get_gene_disease_associationsFree

  Find diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance. Preserves conflicting and limited assertions. Gene-disease validity is not variant pathogenicity or a patient diagnosis. Use only a public gene identifier; no patient or case data. Results require professional review.

• get_publication_detailsFree

  Retrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, and PubMed/PMC links. Use after literature search when a user asks to inspect a specific publication. This is read-only professional literature evidence and contains no patient context.

• search_disease_genesFree

  Find human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source reports and snapshot provenance. Name searches may match multiple diseases; preserve their distinct identities and do not infer a diagnosis. Use only a public disease name or identifier; no symptoms, patient or case data. Results require professional review.

• search_literature_corpusFree

  Semantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence and concepts across the corpus. Also accepts genes, variants, phenotypes, HPO and OMIM concepts. Include every known publication identifier in the query when the user asks to compare papers or find work related to a specific paper. Returns source-linked evidence candidates for professional review, not diagnoses, causality claims or treatment recommendations.

• search_variant_evidenceFree

  Interpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or interpret pathogenicity, review a VUS, check available ClinVar assertions or population-frequency evidence, or resolve a variant notation. Classify, interpret or resolve one public GRCh38 germline SNV or simple indel smaller than 50 bp. Accepts coordinates, genomic/coding/protein HGVS, SPDI or rsID. Returns normalized variant identity, automated ACMG/AMP decision support, evidence, provenance and explicit limitations. This is variant-level decision support for professional review. It does not evaluate patient context and must not be presented as a diagnosis or treatment recommendation. Never choose a candidate when resolution is ambiguous.

• search_variant_literatureFree

  Resolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about a variant, gene or associated condition. Associations do not establish causality, pathogenicity or a diagnosis and do not change Folklore's ACMG/AMP classification.

• support_helenaFree

  Learn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklore scientific result.

• –Code scanremote-only server, no package to scann/a
• Live reliabilityremote reachable in 2443ms17/20
• Tool poisoning7 tool descriptions checked15/15
• Auth qualityopen endpoint, read-only tools10/15
• Maintenancelast push 8 days ago15/15
• Maintainer identityregistry namespace matches repository owner7/10

Folklore Clinical Variant Interpretation MCP: common questions

Is Folklore Clinical Variant Interpretation MCP server safe?

Yes, by our scan: it is graded A (85/100). Read the Folklore Clinical Variant Interpretation MCP safety report

How do I install Folklore Clinical Variant Interpretation MCP?

It runs remotely at api.helena.bio. Add it to Claude Code, Claude Desktop or Cursor with the snippets above, or call it through the mcp.market gateway without installing anything.

Does Folklore Clinical Variant Interpretation MCP need an API key?

Not as far as the registry entry and our scan can tell: no credentials are declared or required.

Is Folklore Clinical Variant Interpretation MCP maintained?

The last commit was 10 days ago (2026-09-11). The latest release is v1.5.0.

Is Folklore Clinical Variant Interpretation MCP up?

100% of our last 7 checks got an answer. We check remote servers about four times a day.